BDBM344235 N-{6-[(3 aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl]-2-isopropoxypyridin-3-yl}-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydrofuro[3,2-c]pyridine-3-carboxamide::US9777020, Example 129

SMILES CC(C)Oc1nc(ccc1NC(=O)c1coc2CC(C)(C)NC(=O)c12)N1C[C@H]2CCN[C@H]2C1

InChI Key InChIKey=GQXSTFVHKVEKBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344235   

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344235(N-{6-[(3 aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1...)
Affinity DataIC50: 10.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
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