BDBM343915 1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(1-(pyrrolidin-3-yl)-1H-benzo[d]imidazol-6-yl)phenoxy)propan-2-ol::US9777008, Compound 209

SMILES OC(COc1cccc(c1)-c1ccc2ncn(C3CCNC3)c2c1)CN1CCc2ccccc2C1

InChI Key InChIKey=PFJXPWUIIXLIKQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343915   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Epizyme

US Patent

LigandBDBM343915(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(1-(pyrro...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2019
Entry Details
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