BDBM343688 3-(1-Benzofuran-2-yl)-6-[(2R)-pyrrolidin-2-ylmethoxy]imidazo[1,2-b]pyridazine::US9777004, 21::US9777004, 23

SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CCCN1

InChI Key InChIKey=GTGOLIIHGCZQES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 343688   

LigandPNGBDBM343688(US9777004, 23 | 3-(1-Benzofuran-2-yl)-6-[(2R)-pyrr...)
Affinity DataIC50: 15nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

LigandPNGBDBM343688(US9777004, 23 | 3-(1-Benzofuran-2-yl)-6-[(2R)-pyrr...)
Affinity DataIC50: 25nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

LigandPNGBDBM343688(US9777004, 23 | 3-(1-Benzofuran-2-yl)-6-[(2R)-pyrr...)
Affinity DataIC50: 44nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

LigandPNGBDBM343688(US9777004, 23 | 3-(1-Benzofuran-2-yl)-6-[(2R)-pyrr...)
Affinity DataIC50: 53nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent