BDBM342719 5-[4-(Pyridine-3-carbonyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid2,4-dichloro-benzylamide::US9776991, Example 89

SMILES Clc1ccc(CNC(=O)c2ccc(CN3CCN(CC3)C(=O)c3cccnc3)s2)c(Cl)c1

InChI Key InChIKey=PIQXLQCBGWMFNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342719   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342719(5-[4-(Pyridine-3-carbonyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 1.40nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
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