BDBM342681 5-[4-(1-Methyl-1H-pyrrole-2-carbonyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid 2-trifluoromethyl-benzylamide::US9776991, Example 51

SMILES Cn1cccc1C(=O)N1CCN(Cc2ccc(s2)C(=O)NCc2ccccc2C(F)(F)F)CC1

InChI Key InChIKey=KQNWBJZSEIVSQC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342681   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent

LigandBDBM342681(5-[4-(1-Methyl-1H-pyrrole-2-carbonyl)-piperazin-1-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.994nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2019
Entry Details
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