BDBM342659 5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-piperazin-1-ylmethyl]-4-methyl-thiophene-2-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-5-ylmethyl)-amide::US9776991, Example 29

SMILES Cc1cc(sc1CN1CCN(CC1)C(=O)c1c(C)cc(=O)oc1C)C(=O)NCc1cccc2OCCOc12

InChI Key InChIKey=NNYLWNFTQBNHAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342659   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342659(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
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