BDBM342631 5-[4-((R)-2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid-trifluoromethoxy-benzylamide::US9776991, Example 1

SMILES C[C@@H](O)C(=O)N1CCN(Cc2ccc(s2)C(=O)N(Cc2ccccc2)OC(F)(F)F)CC1

InChI Key InChIKey=HJLGPZLTZBUAAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342631   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342631(5-[4-((R)-2-Hydroxy-propionyl)-piperazin-1-ylmethy...)
Affinity DataIC50: 0.122nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
Go to US Patent