BDBM342605 N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)phenyl]-2,2,2-trifluoroethanesulfonamide::US9776990, Example 48

SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(=O)(=O)CC(F)(F)F)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=KKNWRQZNTYYEAR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342605   

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342605(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Affinity DataKi:  43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342605(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Affinity DataKi:  68nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent