BDBM342112 3-((4-((4-(3-(1,3-Di-tert-butyl-1H-pyrazol-5-yl)ureido)naphthalen-1-yl)oxy)pyrimidin-2-yl)amino)-5-ethynyl-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)benzamide::US9771353, Example 12

SMILES COCCOCCOCCNC(=O)c1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C(C)(C)C)C(C)(C)C)c4ccccc34)n2)cc(c1)C#C

InChI Key InChIKey=QQNVMVLXXHIOHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342112   

TargetGlycogen synthase kinase-3 alpha(Human)
Topivert Pharma

US Patent
LigandPNGBDBM342112(US9771353, Example 12 | 3-((4-((4-(3-(1,3-Di-tert-...)
Affinity DataIC50: 1.31E+4nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3-alpha enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
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