BDBM341802 1-{2-[(2,6-difluorophenyl)methoxy]-1,1,1,3,3,3-hexafluoropropan-2-yl}-4-[1-(4-fluorobenzenesulfonyl)cyclobutyl]benzene::US9771320, Example 39

SMILES Fc1ccc(cc1)S(=O)(=O)C1(CCC1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=GZVQMFOHFMHLEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341802   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341802(US9771320, Example 39 | 1-{2-[(2,6-difluorophenyl)...)
Affinity DataIC50: 27nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details
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