BDBM341782 (1R,3s,5S)-3-(4-(2-(benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)phenyl)-3-((4-fluorophenyl)sulfonyl)-6-oxabicyclo[3.1.0]hexane::US9771320, Example 19

SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]1(C[C@H]2O[C@H]2C1)c1ccc(cc1)C(OCc1ccccc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=KLPOAURUBTVBBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341782   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341782(US9771320, Example 19 | (1R,3s,5S)-3-(4-(2-(benzyl...)
Affinity DataIC50: 17nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details
Go to US Patent