BDBM341629 1-(5-(2-fluoro-4-methoxyphenyl)-7,8-dihydrothiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)-2-(isoquinolin-7-yloxy)ethanone::US9765092, Example 6.3.3

SMILES COc1ccc(C2N(CCc3nc4sccn4c23)C(=O)COc2ccc3ccncc3c2)c(F)c1

InChI Key InChIKey=BPWZZBCDTGALMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341629   

TargetTryptophan 5-hydroxylase 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341629(US9765092, Example 6.3.3 | 1-(5-(2-fluoro-4-methox...)
Affinity DataIC50: 4nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
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