BDBM341290 6-[(2-{4-[5-Chloro-2-(difluoromethoxy)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}butanoyl)amino]-imidazo[1,2-a]pyridine-2-carboxylic acid (racemate)::US9765070, Example 7

SMILES CCC(C(=O)Nc1ccc2nc(cn2c1)C(O)=O)n1cc(OC)c(cc1=O)-c1cc(Cl)ccc1OC(F)F

InChI Key InChIKey=GJLNJCSBJYJLIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 341290   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM341290(US9765070, Example 7 | 6-[(2-{4-[5-Chloro-2-(diflu...)
Affinity DataIC50: 12nMAssay Description:Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting final con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM341290(US9765070, Example 7 | 6-[(2-{4-[5-Chloro-2-(diflu...)
Affinity DataIC50: 150nMAssay Description:Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting final con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent