BDBM34101 benzamide derivative, 14e

SMILES COc1ccc(NC(=O)CN2CCN(CC2)c2ccc(F)cc2F)cc1OC

InChI Key InChIKey=KSKFCSUNSBSRNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34101   

TargetGlycogen phosphorylase, muscle form(Rabbit)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34101(benzamide derivative, 14e)
Affinity DataIC50: 3.59E+4nMAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34101(benzamide derivative, 14e)
Affinity DataAssay Description:The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details Article
PubMed