BDBM340558 4′-(2-tert-Butylphenoxy)-3′-(3-p-tolylureido)biphenyl-2-carboxylic acid::US9765018, Example 2

SMILES Cc1ccc(NC(=O)Nc2cc(ccc2Oc2ccccc2C(C)(C)C)-c2ccccc2C(O)=O)cc1

InChI Key InChIKey=PIOCFBNLYJMPKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340558   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340558(US9765018, Example 2 | 4′-(2-tert-Butylpheno...)
Affinity DataIC50: 560nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340558(US9765018, Example 2 | 4′-(2-tert-Butylpheno...)
Affinity DataIC50: 70nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production pre-incubated for 1 hr followed by IFN-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed