BDBM340312 (Scheme A): Preparation of [(3S)-3-{[2′-amino-5-fluoro-2-(morpholin-4-yl)-4,5′-bipyrimidin-6-yl]amino}-3-(hydroxymethyl)pyrrolidin-1-yl](1-fluorocyclopropyl)methanone::US9758538, Example 1

SMILES Nc1ncc(cn1)-c1nc(nc(N[C@@]2(CO)CCN(C2)C(=O)C2(F)CC2)c1F)N1CCOCC1

InChI Key InChIKey=LIDOSBIJMNIHPF-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340312   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Pfizer

US Patent

LigandBDBM340312(US9758538, Example 1 | (Scheme A): Preparation of ...)Copy SMILESCopy InChI

Affinity DataKi:  0.0200nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2019
Entry Details
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