BDBM340221 (2S,4R)-N-(3-chloro-2- fluorobenzyl)-1-(2-(3- (cyclopropanecarbonyl)- 1H-indol-1-yl)acetyl)- 4-fluoropyrrolidine-2- carboxamide::US9758537, Compound 24

SMILES F[C@@H]1C[C@H](N(C1)C(=O)Cn1cc(C(=O)C2CC2)c2ccccc12)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=YVYJTTWCBSJCPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340221   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340221(US9758537, Compound 24 | (2S,4R)-N-(3-chloro-2- fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent