BDBM340219 (1R,3S,5R)-N-(3- chloro-2-fluorobenzyl)- 2-(2-(3- (cyclopropanecarbonyl)- 1H-indol-1-yl)acetyl)- 2- azabicyclo[3.1.0]hexane- 3-carboxamide::US9758537, Compound 22

SMILES Fc1c(Cl)cccc1CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1cc(C(=O)C2CC2)c2ccccc12

InChI Key InChIKey=BEZJXSWOSUCIJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340219   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340219(US9758537, Compound 22 | (1R,3S,5R)-N-(3- chloro-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent