BDBM34017 CHEMBL104850::phenylpropanoic acid derivative, 7

SMILES Cc1oc(nc1CCOc1ccc(C[C@@H](C(O)=O)n2cccc2)cc1)-c1ccccc1

InChI Key InChIKey=OCWDFPOKWYMLGH-UHFFFAOYSA-N

Data  5 KI  2 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 34017   

LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataIC50: 29nM EC50:  26nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR gamma ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataIC50: 697nM EC50:  684nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  3.80E+3nMAssay Description:Concentration that gave 50% of maximal reporter activity against human Peroxisome proliferator activated receptor delta Gal4 chimeric in transiently ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  20nMAssay Description:Maximal reporter activity against human Peroxisome proliferator activated receptor gamma Gal4 chimeric in transiently transfected CV-1 cells by funct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  20nMAssay Description:Maximal reporter activity against human Peroxisome proliferator activated receptor gamma Gal4 chimeric in transiently transfected CV-1 cells by funct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  1.30E+3nMAssay Description:Maximal reporter activity against human Peroxisome proliferator activated receptor alpha Gal4 chimeric in transiently transfected CV-1 cells by funct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  1.30E+3nMAssay Description:Maximal reporter activity against human Peroxisome proliferator activated receptor alpha Gal4 chimeric in transiently transfected CV-1 cells by funct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  4.70nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataEC50:  3.63E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataKi:  51nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor gamma using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataKi:  51nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor gamma using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity to bind to human Peroxisome proliferator activated receptor delta using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor alpha using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM34017(CHEMBL104850 | phenylpropanoic acid derivative, 7)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor alpha using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed