BDBM339997 5-(((3S,4S)-4-amino-1,1- dioxidotetrahydro-2H- thiopyran-3-yl)amino)-3-(5- (trifluoromethyl)-1H-indol-2- yl)pyrazine-2-carboxamide::US9775839, 10.2

SMILES N[C@H]1CCS(=O)(=O)C[C@H]1Nc1cnc(C(N)=O)c(n1)-c1cc2cc(ccc2[nH]1)C(F)(F)F

InChI Key InChIKey=JJJPCUDJDDDAJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339997   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM339997(5-(((3S,4S)-4-amino-1,1- dioxidotetrahydro-2H- thi...)
Affinity DataIC50: 0.800nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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