BDBM339958 5-(6-fluoro-1H-indol-3-yl)-N- (2-(methylsulfonyl)ethyl) pyridin-2-amine::US9758505, 28

SMILES CS(=O)(=O)CCNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=AHBKWSKAZWJTHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339958   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339958(US9758505, 28 | 5-(6-fluoro-1H-indol-3-yl)-N- (2-(...)
Affinity DataIC50: 1.50E+3nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
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