BDBM339950 5-(6-fluoro-1H-indol-3-yl)-N- (1-(methylsulfonyl)piperidin- 4-yl)pyridin-2-amine::US9758505, 19

SMILES CS(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=CBKXEHLVBSUEEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339950   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339950(US9758505, 19 | 5-(6-fluoro-1H-indol-3-yl)-N- (1-(...)
Affinity DataIC50: 650nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent