BDBM339948 5-(6-fluoro-1H-indol-3-yl)-N- (piperidin-4-yl)pyridin-2- amine::US9758505, 17

SMILES Fc1ccc2c(c[nH]c2c1)-c1ccc(NC2CCNCC2)nc1

InChI Key InChIKey=HGVOOKDSZWUKIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339948   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339948(US9758505, 17 | 5-(6-fluoro-1H-indol-3-yl)-N- (pip...)
Affinity DataIC50: 870nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent