BDBM339945 N-(1-(5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)piperidin-4- yl)methanesulfonamide::US9758505, 14

SMILES CS(=O)(=O)NC1CCN(CC1)c1ccc(cn1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=NLTLHMCSQSYARM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339945   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339945(US9758505, 14 | N-(1-(5-(6-fluoro-1H-indol-3- yl)p...)
Affinity DataIC50: 970nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent