BDBM339883 US9757383, Example 6::trans-4-[{2-[{[4-({[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl]amino}methyl)phenoxy]acetyl}(methyl)amino]ethyl}(methyl)amino]cyclohexyl hydroxy(di-2-thienyl)acetate

SMILES CN(CCN(C)C(=O)COc1ccc(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1)[C@H]1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1

InChI Key InChIKey=LICFTXXXFSVXLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 339883   

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM339883(US9757383, Example 6 | trans-4-[{2-[{[4-({[(2R)-2-...)
Affinity DataIC50: 34nMAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM339883(US9757383, Example 6 | trans-4-[{2-[{[4-({[(2R)-2-...)
Affinity DataIC50: 1.40nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent