BDBM339876 US9758480, 14::tert-Butyl trans-4-{cis-2-[3-fluoro-4-(5-oxo-2,5-dihydro-1,2,4-oxazol-3-yl)phenylcarbamoyl]-3-phenylpyrrolidine-1-carbonyl}cyclohexylmethylcarbamate

SMILES NC[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@H]([C@H]1C(=O)Nc1ccc(-c2nc(=O)o[nH]2)c(F)c1)c1ccccc1

InChI Key InChIKey=OEGXOTITFFWLTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339876   

TargetCoagulation factor XI(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM339876(US9758480, 14 | tert-Butyl trans-4-{cis-2-[3-fluor...)
Affinity DataIC50: 130nMAssay Description:0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
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