BDBM3398 2-Butanol deriv. 5::2-[3-[[2-(tert-Butylcarbamoyl)phenyl]sulfanyl]-2-hydroxypropyl]naphthalene-1-carboxylic Acid tert-Butyl Amide::N-tert-butyl-2-(3-{[2-(tert-butylcarbamoyl)phenyl]sulfanyl}-2-hydroxypropyl)naphthalene-1-carboxamide

SMILES CC(C)(C)NC(=O)c1ccccc1SCC(O)Cc1ccc2ccccc2c1C(=O)NC(C)(C)C

InChI Key InChIKey=DPXOXISAOYTUJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3398   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals

LigandPNGBDBM3398(2-[3-[[2-(tert-Butylcarbamoyl)phenyl]sulfanyl]-2-h...)
Affinity DataIC50: 2.50E+4nMpH: 5.6 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2005
Entry Details Article
PubMed