BDBM33956 dihydroxy benzoyl naphthyl hydrazone (DHBNH) analogue, 3

SMILES COc1ccc(cc1)C(=O)N\N=C\c1c(OC)ccc2ccccc12

InChI Key InChIKey=FSSNWTAENDFNCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33956   

TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandPNGBDBM33956(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandPNGBDBM33956(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed