BDBM338447 3-[1-[2,5-difluoro-4-[[(3S,6R)-3- methyl-1,1-dioxo-6-phenyl- thiazinan-2-yl]methyl]phenyl]-1- methyl-ethoxy]propane-1,2-diol::US9751873, Example 134

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)C(C)(C)OCC(O)CO

InChI Key InChIKey=KDBWVNWSLJMVMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338447   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338447(3-[1-[2,5-difluoro-4-[[(3S,6R)-3- methyl-1,1-dioxo...)
Affinity DataIC50: 18nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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