BDBM338436 1-[4-[4-[[(6S)-5,5-dioxo-6-phenyl- 5$1{circumflex over ( )}{6}-thia-4-azaspiro[2.5]octan- 4-yl]methyl]-3-fluoro- phenyl]piperazin-1-yl]ethanone::US9751873, Example 123

SMILES CC(=O)N1CCN(CC1)c1ccc(CN2C3(CC3)CC[C@H](c3ccccc3)S2(=O)=O)c(F)c1

InChI Key InChIKey=DHYSFZKRROBYEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338436   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338436(1-[4-[4-[[(6S)-5,5-dioxo-6-phenyl- 5$1{circumflex ...)
Affinity DataIC50: 7nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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