BDBM338424 (3S,6R)-2-[[2,5-difluoro-4-[(3S,4R)- 3-fluoro-4-[(1,2,4-triazol-4-yl)-1- piperidyl]phenyl]methyl]-3-methyl- 6-phenyl-thiazinane 1,1-dioxide::US9751873, Example 111

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)N1CC[C@H]([C@@H](F)C1)n1cnnc1

InChI Key InChIKey=SQCNQJLVQLTVSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338424   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338424((3S,6R)-2-[[2,5-difluoro-4-[(3S,4R)- 3-fluoro-4-[(...)
Affinity DataIC50: 13nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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