BDBM338400 8-[3-fluoro-4-[[3S,6R)-3-methyl- 1,1-dioxo-6-phenyl-thiazinan-2- yl]methyl]phenyl]-1,3-dimethyl- 1,3,8-triazaspiro[4.5]decane-2,4- dione::US9751873, Example 88

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)C1Cc1ccc(cc1F)N1CCC2(CC1)N(C)C(=O)N(C)C2=O

InChI Key InChIKey=URFSGUBVRWEWLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338400   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338400(8-[3-fluoro-4-[[3S,6R)-3-methyl- 1,1-dioxo-6-pheny...)
Affinity DataIC50: 6.90nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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