BDBM338397 (3S,6R)-2-[[2-fluoro-4-[(3R,4R)-3- fluoro-4-(1,2,4-triazol-4-yl)-1- piperidyl]phenyl]methyl]-3-methyl- 6-phenyl-thiazinane 1,1-dioxide::US9751873, Example 85::US9751873, Example 94

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(cc1F)N1CC[C@H]([C@H](F)C1)n1cnnc1

InChI Key InChIKey=HIDIOJFYPYHFRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338397   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338397(US9751873, Example 94 | (3S,6R)-2-[[2-fluoro-4-[(3...)
Affinity DataIC50: 13.9nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338397(US9751873, Example 94 | (3S,6R)-2-[[2-fluoro-4-[(3...)
Affinity DataIC50: 14nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent