BDBM338393 2-(4-((5R)-5-(4H-1,2,4-triazol-4- yl)-2-azabicyclo[2.2.1]heptan-2- yl)-2,5-difluorobenzyl)-3-methyl- 6-phenyl-1,2-thiazinane 1,1-dioxide::US9751873, Example 81::US9751873, Example 82

SMILES CC1CCC(c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)N1CC2CC1CC2n1cnnc1

InChI Key InChIKey=LDVCUQRTQNORBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338393   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338393(US9751873, Example 82 | 2-(4-((5R)-5-(4H-1,2,4-tri...)
Affinity DataIC50: 15nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338393(US9751873, Example 82 | 2-(4-((5R)-5-(4H-1,2,4-tri...)
Affinity DataIC50: 11nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent