BDBM338389 (3R,6R)-2-(4-((1R,5S,6S)-6-(4H- 1,2,4-triazol-4-yl)-3- azabicyclo[3.1.0]hexan-3-yl)-2- fluorobenzyl)-6-phenyl-3- (trifluoromethyl)-1,2-thiazinane 1,1-dioxide::US9751873, Example 77

SMILES Fc1cc(ccc1CN1[C@H](CC[C@H](c2ccccc2)S1(=O)=O)C(F)(F)F)N1CC2[C@H](C1)[C@H]2n1cnnc1

InChI Key InChIKey=DRHUTPBSGMZVPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338389   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338389((3R,6R)-2-(4-((1R,5S,6S)-6-(4H- 1,2,4-triazol-4-yl...)
Affinity DataIC50: 27nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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