BDBM338331 (3S,6R)-2-[2-Fluoro-4-((3R,4S)-3- methyl-4-[1,2,4]triazol-4-yl- piperidin-1-yl)-benzyl]-3-methyl-6- phenyl-[1,2]thiazinane 1,1-dioxide::US9751873, Example 17

SMILES C[C@@H]1CN(CC[C@@H]1n1cnnc1)c1ccc(CN2[C@@H](C)CC[C@H](c3ccccc3)S2(=O)=O)c(F)c1

InChI Key InChIKey=LSHQMJIVDVPWGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338331   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338331((3S,6R)-2-[2-Fluoro-4-((3R,4S)-3- methyl-4-[1,2,4]...)
Affinity DataIC50: 15nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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