BDBM338317 (3S,6R)-2-[2-Fluoro-4-(tetrahydro- pyran-4-ylmethoxy)-benzyl]-3- methyl-6-phenyl-[1,2]thiazinane 1,1- dioxide::US9751873, Example 3

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(OCC2CCOCC2)cc1F

InChI Key InChIKey=LKCVDAJJOWDVJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338317   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338317((3S,6R)-2-[2-Fluoro-4-(tetrahydro- pyran-4-ylmetho...)
Affinity DataIC50: 28nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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