BDBM338050 US9751854, Compound I-225::US9802960, Compound I-225

SMILES COc1nccc(Nc2cc(ccn2)-c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2C)n1

InChI Key InChIKey=GEAJYKZDBROSOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338050   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338050(US9751854, Compound I-225 | US9802960, Compound I-...)
Affinity DataIC50: 10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338050(US9751854, Compound I-225 | US9802960, Compound I-...)
Affinity DataIC50: 10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent