BDBM337801 3-(5-Chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-2,4-dioxo-1-[4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (racemate)::US9751843, 195

SMILES OC(=O)c1cn(-c2ccc(cc2)N2CCOC2=O)c(=O)n(C2CCCc3c(Cl)cccc23)c1=O

InChI Key InChIKey=JNCWZSVHPGNCEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337801   

TargetChymase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337801(3-(5-Chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-2,4...)
Affinity DataIC50: 43nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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