BDBM336813 6-((((S)-1-amino-3-hydroxy-1- oxopropan-2-yl)amino)-methyl)- 2-(4-(4-(trifluoromethyl)- phenoxy)cyclohex-1-en-1- yl)pyrimidine-4-carboxamide::US9745287, Compound 58

SMILES NC(=O)[C@H](CO)NCc1cc(nc(n1)C1=CCC(CC1)Oc1ccc(cc1)C(F)(F)F)C(N)=O

InChI Key InChIKey=GWKJTXNPHIZOFV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336813   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM336813(6-((((S)-1-amino-3-hydroxy-1- oxopropan-2-yl)amino...)
Affinity DataKi:  524nMAssay Description:Cells Manual Electrophysiology: The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DME...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM336813(6-((((S)-1-amino-3-hydroxy-1- oxopropan-2-yl)amino...)
Affinity DataIC50: 1.47E+3nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent