BDBM336761 2-{[(3R,6R)-1- {[4-fluoro-2-(2H- 1,2,3-triazol-2-yl) phenyl]carbonyl}- 6-methylpiperidin- 3-yl]oxy}-4-(1- methylethoxy) pyridine::US9745284, 23

SMILES CC(C)Oc1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(F)cc2-n2nccn2)c1

InChI Key InChIKey=NEZYDUOOYRFBSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336761   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336761(2-{[(3R,6R)-1- {[4-fluoro-2-(2H- 1,2,3-triazol-2-y...)
Affinity DataIC50: 41.2nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336761(2-{[(3R,6R)-1- {[4-fluoro-2-(2H- 1,2,3-triazol-2-y...)
Affinity DataIC50: 2.15E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent