BDBM336701 US9745283, Example 130

SMILES CCC(C)Cn1c(=O)c(nn(C)c1=O)C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1

InChI Key InChIKey=YQYDWEWNOJLGGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336701   

TargetTyrosine-protein kinase receptor UFO(Human)
Ignyta

US Patent
LigandPNGBDBM336701(US9745283, Example 130)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to inhibit the kinase activity of recombinant human baculovirus-expressed AXL was measured by homogeneous TRF (HTRF) using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Ignyta

US Patent
LigandPNGBDBM336701(US9745283, Example 130)
Affinity DataIC50: 55nMAssay Description:The cMET kinase assay was performed in 384-well Fluotrac 200 HiBase microplates using the HTRF KinEASE assay described above for AXL except that the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent