BDBM336581 4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (cyclopropyl (methyl)carbamoyl)-1H- pyrazolo[4,3- b]pyridin-3-yl)-3- fluorobenzoic acid::US9745265, 7D

SMILES CN(C1CC1)C(=O)c1cnc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1F)C(O)=O

InChI Key InChIKey=KPPSRVSRXSXIEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336581   

TargetNuclear receptor ROR-gamma(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336581(4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (c...)
Affinity DataIC50: 14nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent