BDBM336542 1-(5-(pyridin-3- yl)indolin-1- yl)ethanethione::US9745282, 34

SMILES CC(=S)N1CCc2cc(ccc12)-c1cccnc1

InChI Key InChIKey=DBJXPPVQGSTTBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336542   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336542(1-(5-(pyridin-3- yl)indolin-1- yl)ethanethione | U...)
Affinity DataIC50: 6nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
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TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336542(1-(5-(pyridin-3- yl)indolin-1- yl)ethanethione | U...)
Affinity DataIC50: 3.38E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent