BDBM336541 2,2,2-trifluoro-1-(7- fluoro-5-(5- fluoropyridin-3- yl)indolin-1- yl)ethanone::US9745282, 33

SMILES Fc1cncc(c1)-c1cc2CCN(C(=O)C(F)(F)F)c2c(F)c1

InChI Key InChIKey=GVHAYABNPLBFSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336541   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336541(2,2,2-trifluoro-1-(7- fluoro-5-(5- fluoropyridin-3...)
Affinity DataIC50: 17.4nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
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TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336541(2,2,2-trifluoro-1-(7- fluoro-5-(5- fluoropyridin-3...)
Affinity DataIC50: 1.41E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent