BDBM336515 1-(5-(4-ethyl-5- fluoropyridine-3-yl)- 7-fluoroindolin-1- yl)ethanone::US9745282, 20

SMILES CCc1c(F)cncc1-c1cc2CCN(C(C)=O)c2c(F)c1

InChI Key InChIKey=PQEVDZILZGBAMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336515   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336515(1-(5-(4-ethyl-5- fluoropyridine-3-yl)- 7-fluoroind...)
Affinity DataIC50: 1.60nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
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TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336515(1-(5-(4-ethyl-5- fluoropyridine-3-yl)- 7-fluoroind...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent