BDBM336331 1-(7-chloro-5-(5- fluoro-4- methylpyridin-3- yl)indolin-1- yl)ethanone::US9745282, 8

SMILES CC(=O)N1CCc2cc(cc(Cl)c12)-c1cncc(F)c1C

InChI Key InChIKey=GUGLJXBFZXPLPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336331   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336331(1-(7-chloro-5-(5- fluoro-4- methylpyridin-3- yl)in...)
Affinity DataIC50: 1.40nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336331(1-(7-chloro-5-(5- fluoro-4- methylpyridin-3- yl)in...)
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent