BDBM336 (3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-4,5-dihydroxy-7-(3-iodobenzyl)-2-[(N-2-thiazolylcarbamoyl)methyl]-1,2,7-thiadiazepine 1,1-Dioxide::2-[(3R,4S,5S,6R)-4,5-dihydroxy-7-[(3-iodophenyl)methyl]-1,1-dioxo-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepan-2-yl]-N-(1,3-thiazol-2-yl)acetamide::Cyclic Sulfamide deriv. 14

SMILES O[C@@H]1[C@@H](O)[C@@H](COc2ccccc2)N(Cc2cccc(I)c2)S(=O)(=O)N(CC(=O)Nc2nccs2)[C@@H]1COc1ccccc1

InChI Key InChIKey=KVNMMQYWUYFLTJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM336((3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-4,5-dihydroxy...)
Affinity DataKi:  510nM ΔG°:  -8.72kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed