BDBM335728 BDBM50521203::US9738640, Example 3

SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2[nH]ccc2n1

InChI Key InChIKey=XBJFQWTUKHEYQX-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 335728   

TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 1.00E+4nMAssay Description:Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 10.9nMAssay Description:Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-A using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 86nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-B using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

US Patent
LigandPNGBDBM335728(US9738640, Example 3 | BDBM50521203)
Affinity DataKi:  4.80nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed