BDBM335716 N-((6,8-Difluoro-1-methyl-3-oxo- 2,3-dihydroisoquinolin-4- yl)methyl)-5-(ethyl(tetrahydro- 2H-pyran-4-yl)amino)-4-methyl- 4'-(morpholinomethyl)-[1,1'- biphenyl]-3-carboxamide::US9738630, Example 11

SMILES CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c3cc(F)cc(F)c3c(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=SDMGNZSKNHIHSX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335716   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335716(US9738630, Example 11 | N-((6,8-Difluoro-1-methyl-...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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